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Activation of endogenous GABA(A) channels on airway smooth muscle potentiates isoproterenol-mediated relaxation

Reactive airway disease predisposes patients to episodes of acute smooth muscle mediated bronchoconstriction. We have for the first time recently demonstrated the expression and function of endogenous ionotropic GABA(A) channels on airway smooth muscle cells. We questioned whether endogenous GABA(A)...

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Autores principales: Gallos, George, Gleason, Neil R., Zhang, Yi, Pak, Sang-Woo, Sonett, J. R., Yang, Jay, Emala, Charles W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604789/
https://ncbi.nlm.nih.gov/pubmed/18790991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90330.2008
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