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Airway epithelium is a predominant source of endogenous airway GABA and contributes to relaxation of airway smooth muscle tone

Chronic obstructive pulmonary disease and asthma are characterized by hyperreactive airway responses that predispose patients to episodes of acute airway constriction. Recent studies suggest a complex paradigm of GABAergic signaling in airways that involves GABA-mediated relaxation of airway smooth...

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Hlavní autoři: Gallos, George, Townsend, Elizabeth, Yim, Peter, Virag, Laszlo, Zhang, Yi, Xu, Dingbang, Bacchetta, Matthew, Emala, Charles W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567364/
https://ncbi.nlm.nih.gov/pubmed/23204068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00274.2012
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