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BASE EXCISION DNA REPAIR LEVELS IN MITOCHONDRIAL LYSATES OF ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is a senile dementia with increased incidence in older subjects (age>65 years). One of the earliest markers of AD is oxidative DNA damage. Recently it has been reported that preclinical AD patient brains show elevated levels of oxidative damage in both nuclear and mitocho...

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Détails bibliographiques
Publié dans:Neurobiol Aging
Auteurs principaux: Canugovi, Chandrika, Shamanna, Raghavendra A., Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576885/
https://ncbi.nlm.nih.gov/pubmed/24485507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.01.004
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