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BASE EXCISION DNA REPAIR LEVELS IN MITOCHONDRIAL LYSATES OF ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is a senile dementia with increased incidence in older subjects (age>65 years). One of the earliest markers of AD is oxidative DNA damage. Recently it has been reported that preclinical AD patient brains show elevated levels of oxidative damage in both nuclear and mitocho...

詳細記述

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書誌詳細
出版年:Neurobiol Aging
主要な著者: Canugovi, Chandrika, Shamanna, Raghavendra A., Croteau, Deborah L., Bohr, Vilhelm A.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576885/
https://ncbi.nlm.nih.gov/pubmed/24485507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.01.004
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