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The role of DNA repair in brain related disease pathology

Oxidative DNA damage is implicated in brain aging, neurodegeneration and neurological diseases. Damage can be created by normal cellular metabolism, which accumulates with age, or by acute cellular stress conditions which create bursts of oxidative damage. Brain cells have a particularly high basal...

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Main Authors: Canugovi, Chandrika, Misiak, Magdalena, Ferarelli, Leslie K., Croteau, Deborah L., Bohr, Vilhelm A.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720728/
https://ncbi.nlm.nih.gov/pubmed/23721970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2013.04.010
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