BASE EXCISION DNA REPAIR LEVELS IN MITOCHONDRIAL LYSATES OF ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is a senile dementia with increased incidence in older subjects (age>65 years). One of the earliest markers of AD is oxidative DNA damage. Recently it has been reported that preclinical AD patient brains show elevated levels of oxidative damage in both nuclear and mitocho...

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Vydáno v:Neurobiol Aging
Hlavní autoři: Canugovi, Chandrika, Shamanna, Raghavendra A., Croteau, Deborah L., Bohr, Vilhelm A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576885/
https://ncbi.nlm.nih.gov/pubmed/24485507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.01.004
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