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BASE EXCISION DNA REPAIR LEVELS IN MITOCHONDRIAL LYSATES OF ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is a senile dementia with increased incidence in older subjects (age>65 years). One of the earliest markers of AD is oxidative DNA damage. Recently it has been reported that preclinical AD patient brains show elevated levels of oxidative damage in both nuclear and mitocho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Canugovi, Chandrika, Shamanna, Raghavendra A., Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576885/
https://ncbi.nlm.nih.gov/pubmed/24485507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.01.004
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