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DNA base excision repair activities in mouse models of Alzheimer's disease

Alzheimer’s disease (AD) has been correlated with elevated levels of oxidative DNA damage. Base excision repair (BER) is the main repair pathway for the removal of oxidative DNA base modifications. We have recently found significant functional deficiencies in BER in brains of sporadic AD and amnesti...

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Detalhes bibliográficos
Main Authors: Weissman, Lior, de Souza-Pinto, Nadja C., Mattson, Mark P., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763940/
https://ncbi.nlm.nih.gov/pubmed/18378358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.02.014
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