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DNA base excision repair activities in mouse models of Alzheimer's disease

Alzheimer’s disease (AD) has been correlated with elevated levels of oxidative DNA damage. Base excision repair (BER) is the main repair pathway for the removal of oxidative DNA base modifications. We have recently found significant functional deficiencies in BER in brains of sporadic AD and amnesti...

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Détails bibliographiques
Auteurs principaux: Weissman, Lior, de Souza-Pinto, Nadja C., Mattson, Mark P., Bohr, Vilhelm A.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763940/
https://ncbi.nlm.nih.gov/pubmed/18378358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.02.014
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