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BASE EXCISION DNA REPAIR LEVELS IN MITOCHONDRIAL LYSATES OF ALZHEIMER’S DISEASE

Alzheimer’s disease (AD) is a senile dementia with increased incidence in older subjects (age>65 years). One of the earliest markers of AD is oxidative DNA damage. Recently it has been reported that preclinical AD patient brains show elevated levels of oxidative damage in both nuclear and mitocho...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Canugovi, Chandrika, Shamanna, Raghavendra A., Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576885/
https://ncbi.nlm.nih.gov/pubmed/24485507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.01.004
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