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DNA Polymerase β Outperforms DNA Polymerase γ in Key Mitochondrial Base Excision Repair Activities

DNA polymerase beta (POLβ), well known for its role in nuclear DNA base excision repair (BER), has been shown to be present in the mitochondria of several different cell types. Here we present a side-by-side comparison of BER activities of POLβ and POLγ, the mitochondrial replicative polymerase, pre...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:DNA Repair (Amst)
Prif Awduron: Baptiste, Beverly A., Baringer, Stephanie L., Kulikowicz, Tomasz, Sommers, Joshua A., Croteau, Deborah L., Brosh, Robert M., Bohr, Vilhelm A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887074/
https://ncbi.nlm.nih.gov/pubmed/33540226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2021.103050
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