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DNA Polymerase β Outperforms DNA Polymerase γ in Key Mitochondrial Base Excision Repair Activities

DNA polymerase beta (POLβ), well known for its role in nuclear DNA base excision repair (BER), has been shown to be present in the mitochondria of several different cell types. Here we present a side-by-side comparison of BER activities of POLβ and POLγ, the mitochondrial replicative polymerase, pre...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Baptiste, Beverly A., Baringer, Stephanie L., Kulikowicz, Tomasz, Sommers, Joshua A., Croteau, Deborah L., Brosh, Robert M., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887074/
https://ncbi.nlm.nih.gov/pubmed/33540226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2021.103050
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