Control of Treg differentiation by the transcription factors Thpok and LRF

The CD4(+)-lineage specific transcription factor Thpok is required for intrathymic CD4(+) T cell differentiation and, together with its homolog LRF, supports CD4(+) T cell helper effector responses. However, it is not known if these factors are needed for the T regulatory (Treg) arm of MHC-II respon...

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Publié dans:J Immunol
Auteurs principaux: Carpenter, Andrea C., Wohlfert, Elizabeth, Chopp, Laura B., Vacchio, Melanie S., Nie, Jia, Zhao, Yongmei, Shetty, Jyoti, Xiao, Qi, Deng, Callie, Tran, Bao, Cam, Margaret, Gaida, Matthias M., Belkaid, Yasmine, Bosselut, Rémy
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576567/
https://ncbi.nlm.nih.gov/pubmed/28754678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700181
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