Control of Treg differentiation by the transcription factors Thpok and LRF

The CD4(+)-lineage specific transcription factor Thpok is required for intrathymic CD4(+) T cell differentiation and, together with its homolog LRF, supports CD4(+) T cell helper effector responses. However, it is not known if these factors are needed for the T regulatory (Treg) arm of MHC-II respon...

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Udgivet i:J Immunol
Main Authors: Carpenter, Andrea C., Wohlfert, Elizabeth, Chopp, Laura B., Vacchio, Melanie S., Nie, Jia, Zhao, Yongmei, Shetty, Jyoti, Xiao, Qi, Deng, Callie, Tran, Bao, Cam, Margaret, Gaida, Matthias M., Belkaid, Yasmine, Bosselut, Rémy
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576567/
https://ncbi.nlm.nih.gov/pubmed/28754678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700181
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