Selective amplification in methotrexate-resistant mouse cells of an artificial dihydrofolate reductase transcription unit making use of cryptic splicing and polyadenylation sites.

Lignende værker

• Carcinogen-mediated methotrexate resistance and dihydrofolate reductase amplification in Chinese hamster cells.
  af: Kleinberger, T, et al.
  Udgivet: (1986)
• Overproduction of dihydrofolate reductase and gene amplification in methotrexate-resistant Chinese hamster ovary cells.
  af: Flintoff, W F, et al.
  Udgivet: (1982)
• UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells.
  af: Tlsty, T D, et al.
  Udgivet: (1984)
• Dihydrofolate reductase gene amplification-associated shift of differentiation in methotrexate-adapted HT-29 cells
  Udgivet: (1991)
• Transcription of the mouse dihydrofolate reductase gene proceeds unabated through seven polyadenylation sites and terminates near a region of repeated DNA.
  af: Frayne, E G, et al.
  Udgivet: (1984)