Selective amplification in methotrexate-resistant mouse cells of an artificial dihydrofolate reductase transcription unit making use of cryptic splicing and polyadenylation sites.

We have constructed a recombinant ( pMOP ) which is based on the bacterial plasmid pML2 and contains bovine papilloma virus type 1 (BPV 1) sequences linked to an artificial mouse dihydrofolate reductase (DHFR) transcription unit. This unit consists of the SV40 early gene promoter, a complete DHFR co...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijä: Breathnach, R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 1984
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557445/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6202514/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1984.tb01903.x
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