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Carcinogen-mediated methotrexate resistance and dihydrofolate reductase amplification in Chinese hamster cells.

We have investigated different parameters characterizing carcinogen-mediated enhancement of methotrexate resistance in Chinese hamster ovary (CHO) cells and in simian virus 40-transformed Chinese hamster embryo (C060) cells. We show that this enhancement reflects dihydrofolate reductase (dhfr) gene...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Kleinberger, T, Etkin, S, Lavi, S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 1986
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.6.1958
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