Carcinogen-mediated methotrexate resistance and dihydrofolate reductase amplification in Chinese hamster cells.
We have investigated different parameters characterizing carcinogen-mediated enhancement of methotrexate resistance in Chinese hamster ovary (CHO) cells and in simian virus 40-transformed Chinese hamster embryo (C060) cells. We show that this enhancement reflects dihydrofolate reductase (dhfr) gene...
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| Опубликовано в:: | Mol Cell Biol |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
1986
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023913/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.6.1958-1964.1986 |
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