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Structure of the dihydrofolate reductase gene in Chinese hamster ovary cells.

Overlapping recombinant lambda 1059 phages carrying regions of the dhfr locus from the amplified Chinese hamster ovary (CHO) cell clone MK42 have been isolated. In addition, dhfr cDNAs from this cell line have been cloned into plasmid pBR322. Restriction analysis of these recombinant molecules has l...

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Main Authors: Carothers, A M, Urlaub, G, Ellis, N, Chasin, L A
Formato: Artigo
Idioma:Inglês
Publicado: 1983
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC325857/
https://ncbi.nlm.nih.gov/pubmed/6300788
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