S phase-specific synthesis of dihydrofolate reductase in Chinese hamster ovary cells.

We investigated the cell cycle modulation of dihydrofolate reductase (DHFR; tetrahydrofolate dehydrogenase, 7,8-dihydroxyfolate:NADP+ oxidoreductase, EC 1.5.1.3) levels in methotrexate-resistant Chinese hamster ovary cells synchronized by mitotic selection. DNA content and DHFR concentration were an...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Mariani, B D, Slate, D L, Schimke, R T
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320316/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6946445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.8.4985
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