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S phase-specific synthesis of dihydrofolate reductase in Chinese hamster ovary cells.
We investigated the cell cycle modulation of dihydrofolate reductase (DHFR; tetrahydrofolate dehydrogenase, 7,8-dihydroxyfolate:NADP+ oxidoreductase, EC 1.5.1.3) levels in methotrexate-resistant Chinese hamster ovary cells synchronized by mitotic selection. DNA content and DHFR concentration were an...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1981
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6946445/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.8.4985 |
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