Cargando...

Overproduction of dihydrofolate reductase and gene amplification in methotrexate-resistant Chinese hamster ovary cells.

Stable isolates of Chinese hamster ovary cells that are highly resistant to methotrexate have been selected in a multistep selection process. Quantitative immunoprecipitations have indicated that these isolates synthesize dihydrofolate reductase at an elevated rate over its synthesis in sensitive ce...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Flintoff, W F, Weber, M K, Nagainis, C R, Essani, A K, Robertson, D, Salser, W
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1982
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6287233/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.2.3.275
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!