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Transcription of the mouse dihydrofolate reductase gene proceeds unabated through seven polyadenylation sites and terminates near a region of repeated DNA.

We observed equimolar transcription throughout the 35-kilobase mouse dihydrofolate reductase structural gene. Transcription termination occurred within a discrete region (900 base pairs) located 1 kilobase beyond the last of seven functional polyadenylation sites and near a repetitive DNA sequence e...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Frayne, E G, Leys, E J, Crouse, G F, Hook, A G, Kellems, R E
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1984
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369306/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6084812/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.12.2921
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