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Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

Loss of telomeric DNA during cell proliferation may play a role in ageing and cancer. Since telomeres permit complete replication of eukaryotic chromosomes and protect their ends from recombination, we have measured telomere length, telomerase activity and chromosome rearrangements in human cells be...

詳細記述

保存先:
書誌詳細
主要な著者: Counter, C M, Avilion, A A, LeFeuvre, C E, Stewart, N G, Greider, C W, Harley, C B, Bacchetti, S
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC556651/
https://ncbi.nlm.nih.gov/pubmed/1582420
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