Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes.

We have measured telomere length and telomerase activity throughout the life span of clones of human B lymphocytes transformed by Epstein-Barr virus. Shortening of telomeres occurred at similar rates in all populations and persisted until chromosomes had little telomeric DNA remaining. At this stage...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Counter, C M, Botelho, F M, Wang, P, Harley, C B, Bacchetti, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3410-3414.1994
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!