Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes.

We have measured telomere length and telomerase activity throughout the life span of clones of human B lymphocytes transformed by Epstein-Barr virus. Shortening of telomeres occurred at similar rates in all populations and persisted until chromosomes had little telomeric DNA remaining. At this stage...

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Detaylı Bibliyografya
Yayımlandı:	J Virol
Asıl Yazarlar:	Counter, C M, Botelho, F M, Wang, P, Harley, C B, Bacchetti, S
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1994
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3410-3414.1994
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Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes.

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