Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes.

We have measured telomere length and telomerase activity throughout the life span of clones of human B lymphocytes transformed by Epstein-Barr virus. Shortening of telomeres occurred at similar rates in all populations and persisted until chromosomes had little telomeric DNA remaining. At this stage...

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Bibliografiska uppgifter

I publikationen:	J Virol
Huvudupphov:	Counter, C M, Botelho, F M, Wang, P, Harley, C B, Bacchetti, S
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1994
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3410-3414.1994
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