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Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes.

We have measured telomere length and telomerase activity throughout the life span of clones of human B lymphocytes transformed by Epstein-Barr virus. Shortening of telomeres occurred at similar rates in all populations and persisted until chromosomes had little telomeric DNA remaining. At this stage...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Counter, C M, Botelho, F M, Wang, P, Harley, C B, Bacchetti, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236835/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151802/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3410-3414.1994
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