Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
The correlation between telomerase activity and human tumors has led to the hypothesis that tumor growth requires reactivation of telomerase and that telomerase inhibitors represent a class of chemotherapeutic agents. Herein, we examine the effects of inhibition of telomerase inside human cells. Pep...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1999
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24427/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588696/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14276 |
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