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Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends

Ku is a conserved DNA end-binding protein that plays various roles at different kinds of DNA ends. At telomeres, Ku is part of the structure that protects the chromosome end, whereas at broken DNA ends, Ku promotes DNA repair as part of the nonhomologous end-joining (NHEJ) pathway. Here, we present...

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Détails bibliographiques
Auteurs principaux: Stellwagen, Anne E., Haimberger, Zara W., Veatch, Joshua R., Gottschling, Daniel E.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC218076/
https://ncbi.nlm.nih.gov/pubmed/12975323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1125903
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