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Structure-activity relationship studies of G9a-like protein (GLP) inhibitors
Given the high homology between the protein lysine methyltransferases G9a-like protein (GLP) and G9a, it has been challenging to develop potent and selective inhibitors for either enzyme. Recently, we reported two quinazoline compounds, MS0124 and MS012, as GLP selective inhibitors. To further inves...
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| Izdano u: | Bioorg Med Chem |
|---|---|
| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5562403/ https://ncbi.nlm.nih.gov/pubmed/28662962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.06.021 |
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