Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O(6)-methylguanine-DNA methyltransferase

Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment. The exact mechanism by which GBM evades TMZ toxicity is not always related to the expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT), and so remains...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Chang, Kwang-Yu, Hsu, Tsung-I., Hsu, Che-Chia, Tsai, Shan-Yin, Liu, Jr-Jiun, Chou, Shao-Wen, Liu, Ming-Sheng, Liou, Jing-Ping, Ko, Chiung-Yuan, Chen, Kai-Yun, Hung, Jan-Jong, Chang, Wen-Chang, Chuang, Cheng-Keng, Kao, Tzu-Jen, Chuang, Jian-Ying
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561972/
https://ncbi.nlm.nih.gov/pubmed/28822335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.005
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