Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O(6)-methylguanine-DNA methyltransferase

Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment. The exact mechanism by which GBM evades TMZ toxicity is not always related to the expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT), and so remains...

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Bibliografische gegevens
Gepubliceerd in:Redox Biol
Hoofdauteurs: Chang, Kwang-Yu, Hsu, Tsung-I., Hsu, Che-Chia, Tsai, Shan-Yin, Liu, Jr-Jiun, Chou, Shao-Wen, Liu, Ming-Sheng, Liou, Jing-Ping, Ko, Chiung-Yuan, Chen, Kai-Yun, Hung, Jan-Jong, Chang, Wen-Chang, Chuang, Cheng-Keng, Kao, Tzu-Jen, Chuang, Jian-Ying
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561972/
https://ncbi.nlm.nih.gov/pubmed/28822335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.005
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