Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival

BACKGROUND: O(6)-methylguanine-DNA methyltransferase (MGMT) expression in glioblastoma correlates with temozolomide resistance. Dose-intense temozolomide schedules deplete MGMT activity in peripheral blood mononuclear cells; however, no published data exist evaluating the effect of temozolomide sche...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Robinson, C G, Palomo, J M, Rahmathulla, G, McGraw, M, Donze, J, Liu, L, Vogelbaum, M A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939788/
https://ncbi.nlm.nih.gov/pubmed/20628383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605792
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars