Prognostic value of test(s) for O6‐methylguanine–DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide

BACKGROUND: Glioblastoma is an aggressive form of brain cancer. Approximately five in 100 people with glioblastoma survive for five years past diagnosis. Glioblastomas that have a particular modification to their DNA (called methylation) in a particular region (the O(6)‐methylguanine–DNA methyltrans...

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Udgivet i:Cochrane Database Syst Rev
Main Authors: McAleenan, Alexandra, Kelly, Claire, Spiga, Francesca, Kernohan, Ashleigh, Cheng, Hung-Yuan, Dawson, Sarah, Schmidt, Lena, Robinson, Tomos, Brandner, Sebastian, Faulkner, Claire L, Wragg, Christopher, Jefferies, Sarah, Howell, Amy, Vale, Luke, Higgins, Julian P T, Kurian, Kathreena M
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078495/
https://ncbi.nlm.nih.gov/pubmed/33710615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD013316.pub2
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