Temozolomide Treatment for Aggressive Pituitary Tumors: Correlation of Clinical Outcome with O(6)-Methylguanine Methyltransferase (MGMT) Promoter Methylation and Expression

Context: The typically indolent behavior of pituitary tumors is juxtaposed with high rates of tumor cell invasion into adjacent dural structures, and occasional aggressive behavior. Although clinically significant invasion and malignant transformation remain uncommon, there are limited treatment opt...

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Vydáno v:J Clin Endocrinol Metab
Hlavní autoři: Bush, Zachary M., Longtine, Janina A., Cunningham, Tracy, Schiff, David, Jane, John A., Vance, Mary Lee, Thorner, Michael O., Laws, Edward R., Lopes, M. Beatriz S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2010
Témata:
JCEM Online: Hot Topics in Translational Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393383/
https://ncbi.nlm.nih.gov/pubmed/20668043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0441
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