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Temozolomide Treatment for Aggressive Pituitary Tumors: Correlation of Clinical Outcome with O(6)-Methylguanine Methyltransferase (MGMT) Promoter Methylation and Expression

Context: The typically indolent behavior of pituitary tumors is juxtaposed with high rates of tumor cell invasion into adjacent dural structures, and occasional aggressive behavior. Although clinically significant invasion and malignant transformation remain uncommon, there are limited treatment opt...

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Bibliografiske detaljer
Udgivet i:J Clin Endocrinol Metab
Main Authors: Bush, Zachary M., Longtine, Janina A., Cunningham, Tracy, Schiff, David, Jane, John A., Vance, Mary Lee, Thorner, Michael O., Laws, Edward R., Lopes, M. Beatriz S.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393383/
https://ncbi.nlm.nih.gov/pubmed/20668043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0441
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