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NCOG-29. O(6)-METHYLGUANINE DNA METHYLTRANSFERASE (MGMT) PROMOTER METHYLATION STATUS AND THE INCIDENCE OF TEMOZOLOMIDE-INDUCED HEMATOLOGIC TOXICITY: AN ASSOCIATION STUDY

BACKGROUND: Despite the growing body of evidence demonstrating an increased clinical benefit of alkylating agents in glioblastoma patients with O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation, little is known regarding the effect of MGMT status on toxicity. The purpose of this inv...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Strohbusch, Alyssa, Pound, Heather, Regis, Patrick, Cavaliere, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651334/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.567
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