Temozolomide Treatment for Aggressive Pituitary Tumors: Correlation of Clinical Outcome with O(6)-Methylguanine Methyltransferase (MGMT) Promoter Methylation and Expression

Context: The typically indolent behavior of pituitary tumors is juxtaposed with high rates of tumor cell invasion into adjacent dural structures, and occasional aggressive behavior. Although clinically significant invasion and malignant transformation remain uncommon, there are limited treatment opt...

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Опубликовано в: :J Clin Endocrinol Metab
Главные авторы: Bush, Zachary M., Longtine, Janina A., Cunningham, Tracy, Schiff, David, Jane, John A., Vance, Mary Lee, Thorner, Michael O., Laws, Edward R., Lopes, M. Beatriz S.
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2010
Предметы:
JCEM Online: Hot Topics in Translational Endocrinology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393383/
https://ncbi.nlm.nih.gov/pubmed/20668043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0441
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