Temozolomide Treatment for Aggressive Pituitary Tumors: Correlation of Clinical Outcome with O(6)-Methylguanine Methyltransferase (MGMT) Promoter Methylation and Expression

Context: The typically indolent behavior of pituitary tumors is juxtaposed with high rates of tumor cell invasion into adjacent dural structures, and occasional aggressive behavior. Although clinically significant invasion and malignant transformation remain uncommon, there are limited treatment opt...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Bush, Zachary M., Longtine, Janina A., Cunningham, Tracy, Schiff, David, Jane, John A., Vance, Mary Lee, Thorner, Michael O., Laws, Edward R., Lopes, M. Beatriz S.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2010
Assuntos:
JCEM Online: Hot Topics in Translational Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393383/
https://ncbi.nlm.nih.gov/pubmed/20668043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0441
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