Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O(6)-methylguanine-DNA methyltransferase

Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment. The exact mechanism by which GBM evades TMZ toxicity is not always related to the expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT), and so remains...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Redox Biol
Hlavní autoři: Chang, Kwang-Yu, Hsu, Tsung-I., Hsu, Che-Chia, Tsai, Shan-Yin, Liu, Jr-Jiun, Chou, Shao-Wen, Liu, Ming-Sheng, Liou, Jing-Ping, Ko, Chiung-Yuan, Chen, Kai-Yun, Hung, Jan-Jong, Chang, Wen-Chang, Chuang, Cheng-Keng, Kao, Tzu-Jen, Chuang, Jian-Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561972/
https://ncbi.nlm.nih.gov/pubmed/28822335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.005
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky