Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O(6)-methylguanine-DNA methyltransferase

Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment. The exact mechanism by which GBM evades TMZ toxicity is not always related to the expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (MGMT), and so remains...

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發表在:Redox Biol
Main Authors: Chang, Kwang-Yu, Hsu, Tsung-I., Hsu, Che-Chia, Tsai, Shan-Yin, Liu, Jr-Jiun, Chou, Shao-Wen, Liu, Ming-Sheng, Liou, Jing-Ping, Ko, Chiung-Yuan, Chen, Kai-Yun, Hung, Jan-Jong, Chang, Wen-Chang, Chuang, Cheng-Keng, Kao, Tzu-Jen, Chuang, Jian-Ying
格式: Artigo
語言:Inglês
出版: Elsevier 2017
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561972/
https://ncbi.nlm.nih.gov/pubmed/28822335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.005
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