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Distinct cellular phenotype linked to defective DNA interstrand crosslink repair and homologous recombination

Repair of DNA interstrand crosslinks (ICLs) predominantly involves the Fanconi anemia (FA) pathway and homologous recombination (HR). The HR repair system eliminates DNA double strand breaks (DSBs) that emerge during ICLs removal. The current study presents a novel cell line, CL-V8B, representing a...

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Bibliografiska uppgifter
I publikationen:Mol Med Rep
Huvudupphovsmän: Gorniewska, Aleksandra M., Kluzek, Katarzyna, Gackowska, Lidia, Kubiszewska, Izabela, Zdzienicka, Malgorzata Z., Bialkowska, Aneta
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561886/
https://ncbi.nlm.nih.gov/pubmed/28627616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6781
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