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Distinct cellular phenotype linked to defective DNA interstrand crosslink repair and homologous recombination
Repair of DNA interstrand crosslinks (ICLs) predominantly involves the Fanconi anemia (FA) pathway and homologous recombination (HR). The HR repair system eliminates DNA double strand breaks (DSBs) that emerge during ICLs removal. The current study presents a novel cell line, CL-V8B, representing a...
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| Publicado en: | Mol Med Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5561886/ https://ncbi.nlm.nih.gov/pubmed/28627616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6781 |
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