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Loss of Homologous Recombination or Non-homologous End-joining Leads to Radial Formation Following DNA Interstrand Crosslink Damage
High levels of interstrand cross-link damage in mammalian cells cause chromatid breaks and radial formations recognizable by cytogenetic examination. The mechanism of radial formation observed following DNA damage has yet to be determined. Due to recent findings linking homologous recombination and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2535844/ https://ncbi.nlm.nih.gov/pubmed/18758156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000138882 |
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