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Non-homologous end joining in class switch recombination: the beginning of the end
Immunoglobulin class switch recombination (CSR) is initiated by a B-cell-specific factor, activation-induced deaminase, probably through deamination of deoxycytidine residues within the switch (S) regions. The initial lesions in the S regions are subsequently processed, resulting in the production o...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660918/ https://ncbi.nlm.nih.gov/pubmed/19008195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0196 |
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