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Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination

DNA double-strand breaks (DSBs) introduced in the switch (S) regions are intermediates during immunoglobulin class switch recombination (CSR). These breaks are subsequently recognized, processed, and joined, leading to recombination of the two S regions. Nonhomologous end-joining (NHEJ) is believed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Du, Likun, van der Burg, Mirjam, Popov, Sergey W., Kotnis, Ashwin, van Dongen, Jacques J.M., Gennery, Andrew R., Pan-Hammarström, Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605234/
https://ncbi.nlm.nih.gov/pubmed/19075292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081915
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