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Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination

DNA double-strand breaks (DSBs) introduced in the switch (S) regions are intermediates during immunoglobulin class switch recombination (CSR). These breaks are subsequently recognized, processed, and joined, leading to recombination of the two S regions. Nonhomologous end-joining (NHEJ) is believed...

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Detalhes bibliográficos
Main Authors: Du, Likun, van der Burg, Mirjam, Popov, Sergey W., Kotnis, Ashwin, van Dongen, Jacques J.M., Gennery, Andrew R., Pan-Hammarström, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605234/
https://ncbi.nlm.nih.gov/pubmed/19075292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081915
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