Bloom Syndrome Radials are Non-homologous and are Suppressed by Phosphorylated BLM

Biallelic mutations in BLM cause Bloom syndrome (BS), a genome instability disorder characterized by growth retardation, sun sensitivity and a predisposition to cancer. As evidence of decreased genome stability, BS cells demonstrate not only elevated levels of spontaneous sister chromatid exchanges...

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Bibliographic Details
Published in:Cytogenet Genome Res
Main Authors: Owen, Nichole, Hejna, James, Rennie, Scott, Mitchell, Asia, Newell, Amy Hanlon, Ziaie, Navid, Moses, Robb E., Olson, Susan B.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406812/
https://ncbi.nlm.nih.gov/pubmed/25766002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000375247
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