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A Role for The ATP7A Copper Transporter in Tumorigenesis and Cisplatin Resistance

The ATP7A protein is a ubiquitously expressed copper-translocating P-type ATPase that controls cytoplasmic copper concentrations by mediating cellular copper egress. In vitro studies have previously demonstrated that ATP7A abundance in various tumor cell lines is correlated with increased resistance...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cancer
Prif Awduron: Zhu, Sha, Shanbhag, Vinit, Wang, Yanfang, Lee, Jaekwon, Petris, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559955/
https://ncbi.nlm.nih.gov/pubmed/28819394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19029
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