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Metallothioneins regulate ATP7A trafficking and control cell viability during copper deficiency and excess
Copper (Cu) is an essential, yet potentially toxic nutrient, as illustrated by inherited diseases of copper deficiency and excess. Elevated expression of the ATP7A Cu exporter is known to confer copper tolerance, however, the contribution of metal-binding metallothioneins is less clear. In this stud...
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| 發表在: | Sci Rep |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7217913/ https://ncbi.nlm.nih.gov/pubmed/32398691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64521-3 |
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