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A Role for The ATP7A Copper Transporter in Tumorigenesis and Cisplatin Resistance

The ATP7A protein is a ubiquitously expressed copper-translocating P-type ATPase that controls cytoplasmic copper concentrations by mediating cellular copper egress. In vitro studies have previously demonstrated that ATP7A abundance in various tumor cell lines is correlated with increased resistance...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Zhu, Sha, Shanbhag, Vinit, Wang, Yanfang, Lee, Jaekwon, Petris, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559955/
https://ncbi.nlm.nih.gov/pubmed/28819394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19029
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