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Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells

BACKGROUND: Copper homeostasis proteins ATP7A and ATP7B are assumed to be involved in the intracellular transport of cisplatin. The aim of the present study was to assess the relevance of sub cellular localisation of these transporters for acquired cisplatin resistance in vitro. For this purpose, lo...

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Библиографические подробности
Главные авторы: Kalayda, Ganna V, Wagner, Christina H, Buß, Irina, Reedijk, Jan, Jaehde, Ulrich
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442842/
https://ncbi.nlm.nih.gov/pubmed/18565219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-175
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